Preheat your oven to 400 degrees f. and line a large baking sheet with parchment paper.
Trim off the ends of each sprout, remove and discard the outer layer if necessary, then cut in half. Transfer to a large bowl.
In a small bowl, whisk all the seasonings for your marinade together really well with oil and lemon juice
Place your salmon fillets on the prepared parchment paper as shown.
Add about a teaspoon of your seasoning/marinade mixture onto each salmon filet, then rub it in.
Add the remaining seasoning/marinade mixture onto the sprouts and toss well to evenly coat.
Add Brussels sprouts in a single layer on the sheet pan around your salmon as shown in the video.
Bake in your preheated oven for 15 minutes, or just until salmon is flaky and Brussels sprouts are tender-crisp and slightly browned.
Garnish with sesame seeds, and lemon wedges.
Enjoy immediately, or allow to cool for future meal prep.